The Facebook-parent projects 2026 capital expenditure between $US125 billion and $US145 billion, compared with its prior forecast of $US115 billion to $US135 billion.
Shares of the company fell around five per cent in extended trading.
The company also warned that legal and regulatory blowback in the EU and the US "could significantly impact our business and financial results."
"We continue to see scrutiny on youth-related issues and have additional trials scheduled for this year in the US, which may ultimately result in a material loss," the company said.
Meta reported first-quarter revenue of $US56.31 billion, beating the LSEG-compiled analysts' average estimate of $US55.45 billion.
It expects second-quarter revenue of $US58 billion to $US61 billion, largely in line with estimates of $US59.5 billion.
Family daily active people (DAP), a metric Meta uses to track unique users who open any one of its apps in a day, rose four per cent in the first quarter from a year earlier to 3.56 billion.
The results come weeks after Reuters reported first about Meta's plans for sweeping layoffs, as CEO Mark Zuckerberg attempts to aggressively integrate AI into the company's workflows and reshape its workforce around the technology.
Meta, which owns Instagram, WhatsApp and Threads, has been spending heavily on AI infrastructure and high compensation for employees such as those working in its Meta Superintelligence Labs, which released its first AI model called Muse Spark earlier this month.
The company's robust ad platform, which offers tools for automating and personalising advertisers' campaigns, has remained its growth engine and has helped support its investments in AI infrastructure.
Meta launched ads on messaging service WhatsApp and microblogging platform Threads last year, intensifying competition with platforms such as Elon Musk's X. Simultaneously, Instagram's Reels continue to jostle with TikTok and YouTube Shorts in the lucrative short-video market.
For the first time, Meta is projected to overtake Alphabet as the world's biggest online advertiser, with an expected $US243.46 billion in global net ad revenue this year, excluding traffic acquisition costs. The forecast, by research firm Emarketer, puts the Google- and YouTube-parent's annual ad revenue at $US239.54 billion.
Last week, the company expanded the availability of its Meta AI business assistant, designed to help advertisers optimise campaign performance and resolve technical issues through real-time guidance.
Meta is installing new tracking software on US-based employees' computers to capture mouse movements, clicks and keystrokes to train its AI models, part of a broad initiative to build AI agents that can perform work tasks autonomously, Reuters reported last week.
Meanwhile, China ordered Meta to unwind its $US2 billion-plus acquisition of AI startup Manus on Monday, as Beijing tightens scrutiny of US investment in domestic startups developing frontier technologies.