Tighe's recent struggles began in September, 2024, when she tore the ACL in her right knee, having already torn the ACL twice in her left knee earlier in her career.
The 33-year-old made an emotional return from her third knee reconstruction in round nine last season, kicking a goal in a tight win over Melbourne.
But she was ruled out of the final quarter of that match after experiencing pain in her recently reconstructed knee, with the injury continuing to plague her in the six months since.
Fremantle announced on Wednesday they will be placing Tighe on the club's inactive list for the entire 2026 campaign, with the Irish star to instead help out on the coaching front.
Tighe is contracted for 2027, but it remains to be seen whether the Dockers can find a permanent fix to her ongoing knee injury.
"Áine has been incredibly diligent in her rehab, but given the complexities surrounding her knee injury, this decision gives her the best opportunity to prioritise her long-term health," Fremantle's general manager of women's football Claire Heffernan said in a statement.
"While she won't be stepping on field in 2026, it's very important to both Aine and the program that she stays connected to the playing group.
"Aine is a natural leader who is deeply respected by her teammates and staff members."
Fremantle posted a 6-6 record last season to narrowly miss a finals berth on percentage.
Tighe's loss is a huge blow to the club's hopes of clawing their way into the finals for next season.
The 185cm forward has kicked 29.16 from her 34 games - including twice kicking bags of four goals - with her ability to take big contested marks in attack proving crucial.
