The 27-year-old, who grew up in Echuca, was her home region’s sole representative in the race on August 1, as she came out the blocks quickly in green and gold before handing the baton to Chloe Mannix-Power.
From there, Monique Hanlon kept the land down under in contention for a podium place before Torrie Lewis crossed the finish line at Glasgow’s Scotstoun Stadium with a time of 43.09 seconds.
However, this effort was not enough to secure Australia a medal in the event, with Trinidad and Tobago narrowly edging them out with a time of 43.07 to take the bronze in Scotland.
Meanwhile, Canada took silver after posting a time of 42.76 as the Jamaican team comprising of Alana Reid, Jodean Williams, Lavanya Williams and Ashanti Moore claimed gold with a time of 42.65.
Reflecting on the solid showing from Team Australia, Australian Athletics praised the team for their “fighting finish” in the race.
“A fighting finish from the Aussies,” a representative wrote on social media.
“Clean changes all-round gave Lewis the opportunity to chase down the field on the home straight, but Australia ultimately ran out of track, finishing just behind the bronze medal position.”
Meanwhile, Jamaican gold medallist Reid expressed her pride after her team earned the spoils in the event - the nation’s fifth at the Games this year, at the time of writing.
"It's all about trust," she said. "I remember, I think two years back, Shelly [Ann Fraser-Pryce] told us that we must trust each other.
She's been a big source of motivation for our athletes."
Meanwhile Canada's Marie-Eloise Leclair also spoke movingly about the togetherness within her team’s camp.
“I think the beautiful thing is that we're able to learn from each other and we accept to grow together, she said.
“Everyone is always ready to teach and learn. We're very attentive to each other and what we need, but especially to the standards that we set."
Earlier at the Games, Lane also competed in the women's 100m individual sprint, reaching the semi-finals before bowing out.
Speaking on social media following her first week in Glasgow, she looked back over what proved to be a memorable experience, despite falling short of a medal on this occasion.
“Representing Australia in my first individual 100m at a major championships is something I’ve been working towards for years,” she said.
“It’s not the result I was hoping for but I enjoyed it so much regardless.
“Making the semi’s is something I’m proud of. This week taught me a lot, and I’m leaving with belief, clarity, and plenty of motivation for what’s next.”