Paris Saint-Germain coach Thomas Tuchel has confirmed that the club's record scorer Edinson Cavani will miss Tuesday's Champions League match away to Manchester United.
Uruguay striker Cavani, who has scored 192 goals for PSG, sustained a hip muscle injury in Saturday's 1-0 Ligue 1 victory over Bordeaux to add to the side's injury woes before the last-16 first leg.
PSG are already without Neymar, who was ruled out with a foot injury, leaving the French side with only Kylian Mbappe as a world class striking option.
Fullback Thomas Meunier has also been ruled out.
"You cannot replace quality players like this, Neymar is one of the key, key players in Europe and we miss him a lot and now we miss a second key player with Edi," Tuchel told reporters on Monday.
However, he did not expect the French league leaders to change their style of play.
"We miss two key attacking players but to change our identity for that?...I don't know if it's the moment. We are PSG, we are used to playing offensively and creating chances," he said.
Tuchel added that it was wrong to expect Mbappe to make up for the injured South American pair.
"It's not really his job to replace Cavani and Neymar, and he can't do all three things at the same time," said Tuchel.
"I want us to play with courage, play as a team, together, tight knit, fight, ready to suffer.
"And I think I don't really want to talk about the result but we want to score perhaps more than one (goal)."
When the draw was made in December few doubted PSG would get the better of a United side labouring under Jose Mourinho.
But Tuchel admitted his side can no longer be considered clear favourites with Red Devils rejuvenated under Ole Gunnar Solskjaer.
"Over 180 minutes I would say it's 50-50," he said.
"At this level it's the details. It could be a decision of a referee, a yellow or a red that can make the difference.
"It's a close game."